@article {1918, title = {The Essential Oils Constituent of Etlingera flexuosa (Zingiberaceae), An Endemic Plant from Central Sulawesi}, journal = {Pharmacognosy Journal}, volume = {14}, year = {2022}, month = {December 2022}, pages = {842-846}, type = {Research Article }, chapter = {842}, abstract = {

Introduction: The essential oils from rhizomes, pseudostems, and leaves of Etlingera flexuosa, an endemic ginger species of Sulawesi, were studied. Methods: The essential oils were extracted using solvent extraction and hydrodistillation methods and analysed by gas chromatography-mass spectrometry (GC-MS). Results: The percentage yield of volatile compounds obtained from solvent extraction method was higher than hydrodistillation. By solvent extraction, sesquiterpenes were found abundantly in rhizomes, pseudostems, and leaves with the percentage of 34.16\%, 35.20\% and 32.70\%, respectively. The rhizome and pseudostems were found to contain spathulanol with the high percentage of 3.91\% and 3.46\%. Meanwhile, by hydrodistillation, the compounds were dominated by fatty acid compunds with the percentage of 82.26\%, 82.79\% and 76.1\% on rhizome, pseudostems and leaves. Glycerol tricaprylate has the high percentage of 66.76\% and 82.12\% on rhizome and pseudostems, while in leaves, fatty acids 1,2,3-propanetriyl ester-decanoic acid was the highest with the percentage of 61.81\%. Sesquiterpenes was the second with the percentage of 10.36\%, 11.15\%, and 11.61\% in rhizomes, pseudostems, and leaves, respectively. Conclusion: The most essential oils of E. flexuosa was obtained from the solvent extraction method.

}, keywords = {Essential oils, Etlingera flexuosa, Extraction, GC-MS, Hydrodistillation}, doi = {10.5530/pj.2022.14.177}, author = {Ramadanil Pitopang and Ihwan and Muhammad Sulaiman Zubair and Nurhaeni} } @article {1689, title = {The Cytotoxicity Study of Lantana camara Linn Essential Oil on HeLa Cancer Cells Line}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {November 2021}, pages = {1498-1501}, type = {Research Article}, chapter = {1498}, abstract = {

Lantana camara Linn (Verbenaceae) is a natural plant that thrives in tropical climates and is relatively easy to cultivate. In Indonesia, this plant is still often considered as a weed. When held, the unpleasant smell and sticky hand make people dislike this plant even though the flowers are diverse. The essential oil was extracted from the leaves of L. camara by hydrodistillation. This study aimed to see how cytotoxic L. camara essential oil was against HeLa carcinoma cells. This research aimed to discover if L. camara essential oil was cytotoxic to HeLa cancer cells. The GC-MS investigation of an essential oil recognized ten compounds; two main constituents of the oil were Caryophyllene (27.65\%) and Germacrene D (23.01\%). The essential oil showed cytotoxicity on HeLa cervical cancer cell lines. The cytotoxic effect of oil was determined using MTT, IC50 values were 44.86 μg/mL + 0.07

}, keywords = {Cervical cancer, Cytotoxicity, HeLa, Hydrodistillation, Lantana camara}, doi = {10.5530/pj.2021.13.190}, author = {Suryati and Dira Hefni and Fatma Sri Wahyuni and Dachriyanus} }