@article {2494, title = {Tribulus terrestris L. in traditional Mongolian medicine: Medicinal Applications, Phytochemistry, Pharmacology}, journal = {Pharmacognosy Journal}, volume = {17}, year = {2025}, month = {April 2025}, pages = {171-178}, type = {Original Article}, chapter = {171}, abstract = {

Background: Tribulus terrestris L. has traditionally been used in Mongolian medicine for its effects on kidney protection, promotion of urination, and boosting of physical energy. This study investigated the plant{\textquoteright}s historical use, chemical composition, biological effects, and medicinal significance. Methods: A literature review was conducted using classical medical texts, pharmacopoeias, and peer-reviewed articles from international research databases to explore the properties and uses of T. terrestris. Results: Traditional sources, such as book {\textquotedblleft}Essence of spring water, root of the eight-part secret{\textquotedblright}({\textquotedblleft}Rashaan Shim Naiman Gishuun{\textquoteright}t Nuuts Uvdisiin Undes{\textquotedblright}), describe T. terrestris as having sweet and warm properties, mainly used for treating kidney diseases and wind-related disorders (khi). It has traditionally been used to relieve kidney ailments caused by cold, kidney rheumatism, urinary retention, leg and back pain, edema, and male reproductive weakness. Additionally, it is believed to promote urination and enhance the overall vitality. Modern research confirms that T. terrestris exhibits kidney-protective effects owing to its antioxidant, anti-inflammatory, and antimicrobial properties. It also has mild diuretic effects, supports sex hormone production, and enhances sexual functions. Furthermore, their antioxidant properties have potential anti-aging effects. Conclusion: Modern research confirms the traditional use of T. terrestris to support kidney health, promote urination, and boost physical energy intake.

}, keywords = {Diuretic activity, Nephroprotective effect, Physical performance, Traditional Mongolian medicine, Tribulus terrestris L.}, doi = {10.5530/pj.2025.17.21}, author = {Baigalmaa Dovchinsuren and Ariunaa Damdinsuren and Bolor Bayarkhuu and Mandakhnaran Purevkhuu and Otgonbat Batjargal and Boditsetseg Badarch and Enkhjargal Dorjbal} } @article {1418, title = {Nephro- and hepatoprotective effect of Rosmarinus officinalis against damage induced with antiTB drugs using a chronic model}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {May 2021}, pages = {722-729}, type = {Original Article}, chapter = {722}, abstract = {

Nephro- and hepatoprotector effect of MeOH extract from R. officinalis against the liver and kidney damage caused by the mixture of RIF:INH:PZA, using a chronic in vivo model are described. MeOH extract (EMRO) was prepared by maceration process and was administered by oral via during 91 days in male Balb/C mice with RIF:INH:PZA-induced renal/liver damage, using silymarin (SIL) as a positive control. EMRO (250 mg/kg) favoured body weight gain respect to the antiTB group, this gain was better than that shown by the SIL. The AST and ALT values of the group that received the EMRO extract and SIL were similar to that the control group and low compared to the group antiTB with liver damage. In addition, the GPx, CAT and POx values of the group treated with the EMRO were similar to that the control group. In the liver histological analysis, no significant alteration was observed; however, a severe nephritis was observed in anti-TB group (II) and this effect was less in groups III (antiTB/SIL) and IV (antiTB/EMRO). MeOH extract enhances body weight gain and primarily protects the kidney and liver from damage caused by the antiTB drug mixture when was administered for 91 days.

}, keywords = {Antitubercular drug, Hepatoprotection, Methanolic extract, Nephroprotective effect, Rosmarinus officinalis}, doi = {10.5530/pj.2021.13.92}, author = {Siordia-Reyes Georgina A and Cornejo-Garrido Jorge and Jim{\'e}nez-Arellanes M. Adelina} }