@article {2546,
	title = {A Review on Chemical Profile and Pharmacological Properties of Marine Sponge Tectitethya Crypta},
	journal = {Pharmacognosy Journal},
	volume = {17},
	year = {2025},
	month = {September 2025},
	pages = {608-619},
	type = {Original Article},
	chapter = {608},
	abstract = {<p class="rtejustify">Marine sponges have gained recognition as a valuable resource due to their significant pharmacological properties. The investigation of substances produced by sponges has been extensively researched to identify their pharmacological properties. Marine sponges, which are part of the phylum Porifera, are thought to be the main source of marine natural products. Sponges are multicellular organisms that have a number of pores and channels for exchanging water; the secondary metabolites they create are in turn influenced by their specific environmental circumstances. Natural products such as lipids, terpenoids, peptides, alkaloids, and steroids are abundant in the marine sponge genus Tectitethya crypta. These compounds have unique chemical structures and have shown promising biological activities, making them ideal candidates for the development of novel drugs to treat various ailments. Tectitethya crypta is a sessile filter-feeder that produces a variety of bioactive compounds, including nucleosides and other secondary metabolites. This article reviews the biology and chemistry of Tectitethya crypta and serves as an introduction to the organism. We discuss the taxonomic classification, morphology, and microenvironment of the sponge, as well as the chemical structures and biological activities of its bioactive compounds. Tectitethya crypta was the source for the development of vidarabine, ara-C, and gemcitabine, which are used to treat viruses and cancer, respectively. We discussed about how these molecules may be used to treat parasitic and infectious disorders.</p>
},
	keywords = {Anticancer drugs, Antiviral drugs, Bioactive compounds, Marine sponges, pharmacological properties},
	doi = {10.5530/pj.2025.17.76},
	author = {Durga Prasad Kondeti and T. Sundarrajan}
}
@article {1267,
	title = {Encouraging Leads from Marine Sources for Cancer Therapy A Review Approach},
	journal = {Pharmacognosy Journal},
	volume = {12},
	year = {2020},
	month = {September 2020},
	pages = {1475-1481},
	type = {Review Article},
	chapter = {1475},
	abstract = {<p class="rtejustify">Cancer is one of the dreadful illnesses that cause mortality in many individuals around the world. Present cancer treatments generally include surgery, radiation therapy with chemotherapy. One of the primary sources of anticancer drugs are natural products that exhibit impressive potential in medicines. Plant and microbial secondary metabolites are an important source for cancer drug development. The ocean has an immense collection of flora and fauna overflowing with natural compounds having potent pharmaceutical significance. Marine bioprospecting has just started recently hence, marine ecosystem has not yet been explored properly. Nearly 68 percent of the drugs derived from marine sources are utilized for cancer and the remaining are utilized for inflammation, pain relief etc. Ongoing advancement in synthetic processes has helped in solving the limitations caused due to the complicated structure of natural products. Unlimited potent sources of compounds that can be isolated having diverse structures are found in the marine biodiversity. Only 1\% of the marine microorganisms have been distinguished till now. Coral reefs and mangrove ecosystem have been focused for bioprospecting on the grounds that they have an elevated level of biodiversity. This review focuses on pharmacologically active anti-cancer lead discovery from marine ecosystem. The review has also tried to describe the structure</p>
},
	keywords = {Algae, Anti-cancer activity, Marine sponges, Natural sources},
	doi = {10.5530/pj.2020.12.202},
	author = {N Srinivasan and S Dhanalakshmi and P Pandian}
}
