@article {1726,
	title = {Online Survey: Prevalence and Attitude of Jordanians Towards Using Herbal Remedies in the Pandemic COVID-19},
	journal = {Pharmacognosy Journal},
	volume = {13},
	year = {2021},
	month = {December 2021},
	pages = {1632-1638},
	type = {Original Article},
	chapter = {1632},
	abstract = {<p class="rtejustify">Coronavirus disease 2019 (COVID-19) is a new virus caused by SARS-CoV-2, a coronavirus from the coronavirus family, that can provoke severe respiratory syndrome. The disease became a pandemic in December 2019. Impaired immune modulation is one of the processes implicated in its pathogenesis, which contributes to poor COVID-19 outcomes. Many investigations have been conducted using medication to control coronaviral infections as antiviral agents or immunomodulators. The results of these tests, however, demonstrated that these medications were useless in fighting the disease. Some people believe that using herbal immunomodulators can aid in the prevention or even curing of COVID-19. Based on prior research, in the management of COVID-19, several botanicals may be useful. We go over the patient attitude and benefits of using such herbal remedies in the regimen of treating COVID-19 in Jordan.</p>
},
	keywords = {Botanicals., Coronavirus, COVID-19, Herbal immunomodulators, Herbal remedies, Pandemic, SARS-CoV-2},
	doi = {10.5530/pj.2021.13.210},
	author = {Noha Abd Alkareem Younis Younis and Rania Mohammad Hamam and Amal Mayyas}
}
@article {1241,
	title = {Phytotherapeutic Evidence Against Coronaviruses and Prospects for COVID-19},
	journal = {Pharmacognosy Journal},
	volume = {12},
	year = {2020},
	month = {September 2020},
	pages = {1252-1267},
	type = {Original Article},
	chapter = {1252},
	abstract = {<p class="rtejustify">The emergence of the novel β-coronavirus (SARS-CoV-2) and subsequent outbreak of COVID-19, is a global health challenge with no known treatment to date and has culminated in significant morbidity and mortality. This article highlights current understanding on SARSCoV- 2 based on the available scientific evidence on human coronavirus (HCoV) infections, which could offer novel insights and therapeutic targets for SARS-CoV-2, the causative agent of COVID-19. Specifically, the paper presents available phytotherapeutic evidence against pathogenic HCoVs with a view to identifying potent plant-derived antiviral agents that could be developed to aid the fight against coronaviruses and the current COVID-19. Evidently, elucidation of CoV integral proteins such as the spike protein, angiotensin-converting enzyme 2, 3C-like cysteine protease and papain-like protease, as good targets for drug developments has lent credence to the use of medicinal plants or their metabolites as prophylaxis or treatment interventions in CoV infections and holds promising ground for SARS-CoV-2. While some promising phytocompounds are currently under clinical trials for COVID-19, increased research into plants and in-depth characterization of their metabolites could reveal more interesting results that would benefit humanity in its fight against emerging and re-emerging viral infections including the current COVID-19. Overall, given the current body of evidence on the potential development of phytotherapeutics for COVID-19, fears need to be allayed while clinical trials continue. Conclusively, the lockdown and other preventive measures which have been implemented in most parts of the world should be humanely exercised and supported to ensure compliance and safety of lives.</p>
},
	keywords = {Antivirals, Coronavirus, COVID-19, Drug target, Natural products, Plant metabolites, Plants, SARS-CoV-2},
	doi = {10.5530/pj.2020.12.174},
	author = {Abdullahi Temitope Jamiu and Christiana Eleojo Aruwa and Ismail Abiodun Abdulakeem and Abdulwakeel Ayokunnun Ajao and Saheed SABIU}
}
