@article {906, title = {Exploration of Anti-Urolithiasis Potential of Traditional Siddha Formulations Amukkara Chooranam and Karisalai Karpam Chooranam by Struvite Crystal Growth Inhibition Assay}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {July 2019}, pages = {683-688}, type = {Original Article}, chapter = {683}, abstract = {

Background: Urolithiasis is a medical condition characterized by formation of stone which comprises of calcium oxalate, magnesium ammonium phosphate and uric acid. Reoccurrence becomes the primary hindering factor in providing relief for urolithiasis; hence there is a need of alternate therapeutic strategy that may effectively combat and halt the formation and nucleation of the crystals. Objective: The main aim of the present investigation is to explore the anti-urolithiasis potential of the two versatile siddha formulations Amukkara Chooranam (AKC) and Karisalai Karpam Chooranam (KKC) using diffusion gel growth technique. Materials and Methods: Silica hydrogel matrix was divided in to three groups which were control, AKC and KKC treated groups. Test drugs were screened at two dose levels of 0.5\% and 1\%. The efficiency of the formulations was screened by comparing the crystal size of the control and treatment medium. Results: The average size of the crystals in the control medium was found to be 2.12 {\textpm} 0.22 cm, whereas the crystal size was significantly decreased in medium contains 0.5\% and 1\% of AKC with the size of 1.4 {\textpm} 0.15 and 1.14 {\textpm} 0.18 cm. Similar type of findings were observed in medium consist of 0.5\% and 1 \% KKC with the size of 1.52 {\textpm} 0.13 and 1.08 {\textpm} 0.17 cm. Conclusion: Results clearly indicates that both the siddha formulations offers maximum percentage inhibition on the crystal growth in the tested medium, this efficacy may be due to presence of versatile phytocomponents present in the formulations.

}, keywords = {Amukkara Chooranam, Crystals, Karisalai karpam chooranam, Lithotripsy, Polyherbal, Traditional medicines}, doi = {10.5530/pj.2019.11.108}, author = {D.Sivaraman and N.Anbu and N.Kabilan and M.Pitchiah Kumar and P.Shanmugapriya and G.J.Christian} } @article {929, title = {The Potential Herbs of Medicinal Forests from Central Kalimantan as a Inhibitor of Staphylococcus aureus}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {July 2019}, pages = {740-744}, type = {Original Article}, chapter = {740}, abstract = {

Background: Central Kalimantan is one of the largest provinces in Indonesia with a wealth of medicinal herbaceous plant species. This province was the origin of various medicinal plants such as tabat barito, akar kuning, pasak bumi and some other medicinal plants that were useful for human health. Methods: This paper explain about inhibitory test extracts etanol of Hati Tanah (Angiotepris Sp) tubers and Sangkareho leaves (Callicarpa longifolia Lam.) in Staphylococcus aureus bacteria with concentration 1\%, 5\%, 10\%, and 15\%. Both plants has been utilized by the community as a traditional medicine to treat minor to moderate injuries such as postpartum. Results: The results for extract Hati Tanah was 15.63 mm, 16.97 mm, 25.42 mm, 28.40 mm and the results for and Sangkareho leaves was 1 mm, 2.68 mm, 3.9 mm, 6.2 mm. Inhibitory test studies have also been performed on the N-Butanol fraction from ethanol extract Hati Tanah tubers of the soil at the same concentrations and bacteria. The inhibited zone results was 15.65 mm, 23.20 mm, 24.15 mm, 26.25 mm. Conclusion: Medicinal forest plants origin of Central Kalimantan is Hati Tanah tubers and Sangkareho leaves has potential as a traditional medicine in inhibiting and killing Staphylococcus aureus bacteria.

}, keywords = {Inhibitory test, Medicinal forest, Staphylococcus aureus, Traditional medicines}, doi = {10.5530/pj.2019.11.117}, author = {Rezqi Handayani} }