@article {1938, title = {The Serum Formulation of Hati Tanah Tuber Ethanol Extract from Central Kalimantan}, journal = {Pharmacognosy Journal}, volume = {14}, year = {2022}, month = {January 2023}, pages = {978-982}, type = {Research Article }, chapter = {978}, abstract = {

Introduction: Lately, the use of natural cosmetics can have a good effect on the skin. One of them is traditional beauty treatments. The Serum is a preparation with low viscosity, because of its low viscosity serum is categorized as an emulsion preparation. From the results of research that has been carried out, ethanol extract of Hati Tanah tuber has great potential as an anti-acne because it can inhibit the growth of acne-causing bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes. With the innovation of serum ethanol extract of Hati Tanah tuber, it can be an option for the community later in the treatment of acne. Methods: The formulation is made in 4 (four) formulas with different concentrations of the main ingredients used. Next is to weigh all the ingredients needed according to each formula. Then physical properties test performed. a) Organoleptic test; b) Homogeneity Test; c) pH test; d) Spreadability Test and e) Adhesion Test. Results: The organoleptic test was carried out directly by looking at the shape and color and smelling the serum preparation of the ethanol extract of Tanah Hari tubers. The test results show that at F0 (0\%) the color is clear, for F1 (0,5\%) it is quite pale pink, F2 (1\%) is bright pink and F3 (5\%) is dark red. For scent organoleptic, F0 indicates no scent, for F1 and F2 there is a distinctive scent from the Hati Tanah tuber which is slightly pungent, while F3 shows a pungent aroma typical of the Hati Tanah tuber. The resulting serum has a thick texture at F0 and F1, a watery texture at F2 and a thinner texture at F3. All of the formulas have met the physical test requirement of organoleptic properties, homogeneity, pH, and adhesion test. Conclusion: The simplicia of Hati Tanah tuber can be made into an innovative cosmetic preparation in the form of serum with a concentration of 0,5\%, 1\% and 5\%. From the results of testing the physical properties of the formulations, all of the formulas have met the physical test requirement of organoleptic properties, homogeneity, pH, and adhesion test.

}, keywords = {Formulation, Hati Tanah Tuber Ethanol Extract., Serum}, doi = {10.5530/pj.2022.14.199}, author = {Nurul Qamariah and Rezqi Handayani and Jessika Maretania} } @article {1114, title = {Formulation and Evaluation of Safety and Antifungal Efficacy of Syzigium Aromaticum-Base Cream on Guinea Pigs Infected with Trichophyton Mentagrophytes}, journal = {Pharmacognosy Journal}, volume = {12}, year = {2020}, month = {March 2020}, pages = {342-350}, type = {Research Article}, chapter = {342}, abstract = {

Background: The increasing incidence of dermatophytoses in the world and the side effects of the current therapies encouraged the search of alternative drugs. Hence the objective of this work was to determine antidermatophytes activity of Syzigium aromaticum formulate antidermatophytic cream. Materials and Methods: The extracts were prepared by maceration of plant materials into methanol. Three formulations of creams were made, and the best was chosen according to its physicochemical stability and appearance. The acute dermal toxicity and antidermatophytic efficacy of the cream was performed on guinea-pig. Results: The methanolic extract of S. aromaticum was incorporated in the final cream formulation. The formulation containing shea-butter 58.5\%, acetylic alcohol 2.5\%, stearic acid 1.5\%, bee-wax 10\%, borax 1.5\%, polysorbate 60 2.5\%, 2 drops of lactic acid and water was chosen because of its good appearance and stability. The cream with methanolic extract of S. aromaticum did not reveal any dermal toxic effect. The cream efficacy was dose-dependent. The treatment with cream at 5\% methanolic extracts of S. aromaticum revealed the best potency after 14 days of treatment. Conclusion: These results show that the cream at 5\% methanolic extract of S. aromaticum seed is promising in the treatment of dermatophytoses and could be used as an alternative in the development of a new therapy.

}, keywords = {Antidermatophytes activity, Cream, Dermatophytes, Formulation, S. aromaticum, Toxicity}, doi = {10.5530/pj.2020.12.54}, author = {Roger Ducos Youmsi Fokouo and Patrick Valere Tsouh Fokou and Cedric Derick Jiatsa Mbouna and Elisabeth Zeuko{\textquoteright}o Menkem and Fabrice Fekam Boyom} } @article {688, title = {Physicochemical Standardization of Polyherbal Powder Formulation: Safoof-e-Makhana}, journal = {Pharmacognosy Journal}, volume = {10}, year = {2018}, month = {August 2018}, pages = {899-906}, type = {Original Article}, chapter = {899}, abstract = {

Introduction: Safoof-e-Makhana (SM) is a Unani polyherbal powder formulation used to treat Sexual disorders. Formulation consists of following herbs Orchis latifolia, Hygrophila auriculata, Asparagus racemosus and Elettaria cardamomum. The main aim of this study was to standardize Safoof-e-Makhana (SM), on the basis of organoleptic characters and physico-phytochemical analysis. Methods: The drugs were cleaned, dried in shade and powdered by passing through sieve $\#$ no. 80 as per the method described in UPI / National Formulary of Unani Medicine. This Safoof formulation was evaluated using physicochemical tests: powder characterization, extractive value, alcohol and water soluble matter, Ash value, LOD at 1050C, pH and HPTLC fingerprinting. Statistical analysis used: Mean \± SEM. Results: Organoleptic characters of the formulation are light brown colour, characteristic odour, sweet taste and moderately fine texture. Physicochemical parameters displayed water soluble extractive (21.83 \± 0.08), alcohol soluble extractive (7.87 \± 0.09), total ash (4.76 \± 0.08), acid insoluble ash (3.36 \± 0.01), water soluble ash (0.89 \± 0.25), LOD at 105oC (11.38 \± 0.34), pH of 1\% and 10\% solution were 6.6 \± 0.1 and 6.0 \± 0.1 respectively. Phytochemical qualitative analysis displayed presence of alkaloids, tannins, flavanoids, steroids, terpenoids, carbohydrates, volatile oil. HPTLC fingerprinting data was also set in. Conclusion: The standardization of this formulation was done and the data obtained would be used as a standard for future reference.\ 

}, keywords = {Formulation, Physicochemical, Polyherbal, Powder, Safoof-e- Makhana, standardization, Unani Medicine}, doi = {10.5530/pj.2018.5.151}, author = {Gazi Jahangeer Rather and Hamiduddin and Mohd Ikram, Shaista Fatima and MD Naquibuddin} }