@article {1129, title = {Chemometric Analysis of Arbutin Derivatives from Paederia foetida and Vitis vinifera with Fourier Transform Infrared (FTIR)}, journal = {Pharmacognosy Journal,}, volume = {12}, year = {2020}, month = {May 2020}, pages = {436-441}, type = {Original Article}, chapter = {436}, abstract = {

Introduction: Paederia foetida and Vitis vinifera were reported to have antioxidant activities due to their polyphenolic phytochemical contents. Arbutin may be included as active compounds in the plants. The chemometric analysis is used to identify the similarity of functional groups found in arbutin and that are in Paederia foetida and Vitis vinifera. Materials and Method: The ethanol extracts of Paderia foetida and Vitis vinifera were subjected to compound partition and characterization. Then a liquid-liquid partition is carried out using n-hexan and water solvents, followed by ethyl acetate and water partitions. This procedure is carried out continuously until the top layer is cleared. Partitioned compounds were analyzed using FTIR spectroscopy to identify functional groups. Furthermore, it was analyzed using the chemometric method (Principal Component Analysis and Cluster Analysis). Results: From the results of FTIR spectroscopy, functional groups in Paederia foetida and Vitis vinifera were identical to functional groups found in arbutin. PCA Analysis was achieved using principal component accounting an eigenvelue about 99,3 \% of the total variance. Conclusions: CA analysis showed that compounds in Paederia foetida (Euclidean distance 0.537) and Vitis Vinifera (Euclidean distance 1.157) may be similar with arbutin.

}, keywords = {Arbutin, Chemometrics, Paederia foetida, PCA, Vitis vinifera}, doi = {10.5530/pj.2020.12.67}, author = {Yusnita Rifai and Mukhriani and Yulia Y Djabir and Gemini Alam} } @article {594, title = {Extraction of Total Phenolics, Flavonoids and Tannins from Paederia foetida L. Leaves and their Relation with Antioxidant Activity}, journal = {Pharmacognosy Journal}, volume = {10}, year = {2018}, month = {March 2018}, pages = {541-547}, type = {Original Article}, chapter = {541}, abstract = {

Introduction: Paederia foetida L. is a climbing shrub that possesses several ethnomedicinal uses with immense pharmacologic relevance. Objective: The study aims to determine an efficient extraction condition for phenolic compounds with substantial antioxidant activity. Materials and Methods: Solvent (aqueous, methanol, ethanol and acetone) extracts were made from fresh leaves (FL) and shade dried leaves (SDL) of P. foetida with different durations (12, 24, 36 and 48 h). Quantitative estimations of all extracts were made for total phenolic content (TPC), total flavonoid content (TFC) and total tannin content (TTC) along with their total antioxidant activity (TAA). The phenolic contents of different extracts were correlated with their TAA. Extracts with highest phenolic yield and TAA estimates for each solvent were assessed by 2, 2-diphenyl-1-picrylhydrazyl (DPPH), 2, 2ˊ-azinobis-3-ethylbenzthiazoline-6- sulfonic acid (ABTS), superoxide (SO) and ferric reducing antioxidant power (FRAP) assays. Results: Methanol exhibited the highest extraction ability for TPC, TFC and TAA while aqueous extractions are superior for TTC. The maximum estimates of all the studied components are noted at 48 h. Mostly, extracts of SDL are superior to FL. TPC and TFC are interrelated between themselves as well as showed positive and significant correlation with TAA. The antioxidant assays (DPPH, ABTS, SO and FRAP) reveal higher antioxidant activity with methanolic extracts compared to other studied solvents. Conclusion: The study highlights antioxidant properties of phenolics, particularly flavonoids in P. foetida, which can be further explored for its pharmacological importance.

}, keywords = {Antioxidants, Extraction conditions, Fresh and shade dried leaves, Paederia foetida, Polyphenols}, doi = {10.5530/pj.2018.3.88}, url = {http://fulltxt.org/article/521}, author = {Shaswat Ojha and Adarsha Raj and Alokesh Roy and Sudipta Roy} } @article {560, title = {Extraction of Total Phenolics, Flavonoids and Tannins from Paederia foetida L. Leaves and their Relation with Antioxidant Activity}, journal = {Pharmacognosy Journal}, volume = {10}, year = {2018}, month = {x}, pages = {XX-XX}, type = {x}, chapter = {XX}, abstract = {

Introduction: Paederia foetida L. is a climbing shrub that possesses several ethnomedicinal uses with immense pharmacologic relevance. Objective: The study aims to determine an efficient extraction condition for phenolic compounds with substantial antioxidant activity. Materials and Methods: Solvent (aqueous, methanol, ethanol and acetone) extracts were made from fresh leaves (FL) and shade dried leaves (SDL) of P. foetida with different durations (12, 24, 36 and 48 h). Quantitative estimations of all extracts were made for total phenolic content (TPC), total flavonoid content (TFC) and total tannin content (TTC) along with their total antioxidant activity (TAA). The phenolic contents of different extracts were correlated with their TAA. Extracts with highest phenolic yield and TAA estimates for each solvent were assessed by 2, 2-diphenyl-1-picrylhydrazyl (DPPH), 2, 2ˊ-azinobis-3-ethylbenzthiazoline-6- sulfonic acid (ABTS), superoxide (SO) and ferric reducing antioxidant power (FRAP) assays. Results: Methanol exhibited the highest extraction ability for TPC, TFC and TAA while aqueous extractions are superior for TTC. The maximum estimates of all the studied components are noted at 48 h. Mostly, extracts of SDL are superior to FL. TPC and TFC are interrelated between themselves as well as showed positive and significant correlation with TAA. The antioxidant assays (DPPH, ABTS, SO and FRAP) reveal higher antioxidant activity with methanolic extracts compared to other studied solvents. Conclusion: The study highlights antioxidant properties of phenolics, particularly flavonoids in P. foetida, which can be further explored for its pharmacological importance.

Key words: Antioxidants, Extraction conditions, Fresh and shade dried leaves, Paederia foetida, Polyphenols.

}, keywords = {Antioxidants, Extraction conditions, Fresh and shade dried leaves, Paederia foetida, Polyphenols.}, doi = {10.5530/jppcm.2018.2s.xx}, author = {Shaswat Ojha and Adarsha Raj and Alokesh Roy and Sudipta Roy} }