@article {233, title = {In-vivo Hepatoprotective Activity of Methanolic Extracts of Sphaeranthus amaranthoides and Oldenlandia umbellate}, journal = {Pharmacognosy Journal}, volume = {9}, year = {2017}, month = {November 2016}, pages = {98-101}, type = {Original Article}, chapter = {98}, abstract = {
Objective: The present study was carried out to evaluate the in vitro hepatoprotective activity of unexploited plants, Sphaeranthus amaranthoides and Oldenlandia umbellate\ on CCl4 induced liver injury, which are indigenous to South India. Methods: in the present study the methanolic extracts from Sphaeranthus amaranthoides and Oldenlandia umbellata were studied against the carbon tetrachloride hepatotoxicity. Results: significant hepatoprotective effect was obtained against carbon tetrachloride induced liver damage as judged from serum marker enzyme activities (SGOT, SGPT, ALT, and TB) and a normal architecture of liver compare to toxic control. Conclusion: the result revealed that methanolic extracts of Sphaeranthus amaranthoides and Oldenlandia umbellata could be useful in preventing CCl4 induced liver injury.
}, keywords = {ALP, CCl4, Hepatoprotective activity, Oldenlandia umbellata, SGOT, SGPT, Sphaeranthus amaranthoides, TB.}, doi = {10.5530/pj.2017.1.16}, author = {Somnath De and Ramalingam Suresh and Akula Murali Sri Sudhakar Babu and Siddabathuni Aneela} }