@article {2321, title = {Biomarker Profiles Associated with Covid-19 Mortality in East Java, Indonesia: A Tertiary Care Hospital Study}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {June 2024}, pages = {689-694}, type = {Research Article}, chapter = {689}, abstract = {

Objective: This study aimed to compare the most useful biomarkers for predicting prognosis and response to therapy in COVID-19 patients. Material and Methods: This quantitative study involved 639 patients who were hospitalized with COVID-19 infection. Patients without any biochemical marker result; patients referred to another hospital; and peripheral oxygen levels measured using oxygen supplementation were excluded from the study. Results: There was a statistically significant difference in terms of demographics, vital signs on admission, and laboratory parameters. The risk of mortality in COVID-19 is significantly influenced by c-reactive protein (CRP) and interleukin-6 (IL-6) levels (p-value \<0.05). Conclusion: Findings revealed these biomarkers could help the future development of more personalized treatment and diagnostic approaches.

}, keywords = {Biomarker, COVID-19, Outcome}, doi = {10.5530/pj.2024.16.110}, author = {Retno Budiarti and Ediono and Muhammad Miftahussurur and Abdulloh Machin and Mochammad Wijdan Rosyich and Ayu Imamatun Nisa and Fatimatuzzahro and Nila Novia Putri and Muhammad Ja{\textquoteright}far Shodiq} }