@article {2365, title = {Cadre Assistance in Improving the Nutritional Status of Two Years Baby: A Literature Review}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {August 2024}, pages = {960-965}, type = {Review Article}, chapter = {960}, abstract = {

Background: The Health Law mandates that efforts to improve community nutrition aim to improve the nutritional quality of individuals and society. Indonesia is still a country with a fairly high category of nutritional problems. Very underweight badgers were 1.2\% and underweight badgers were 5.2\%. Overcoming nutritional problems must involve various parties in society, one of the community parties who plays an important role in overcoming nutritional problems for toddlers is health cadres in the village, especially nutritional problems for toddlers. Objective: to identify and explain scientific evidence regarding Mentoring Efforts by Cadres to improve Nutrition for Baduta and strengthen the theoretical basis that can support solving the problem being researched. Method: Using online journal databases that can be accessed in PDF form, namely, Pubmed, Elsevier/Scopus, Crossref and Google Scholar. Other sources such as textbooks, national health reports, and dissertations. The search included studies published in the last 10 years (2012{\textendash}2022). Using keywords (Kader, Nutrition Baduta, Posyandu Cadre, Cadre, Health Workers, Nutrition Health Workers). Appropriate articles were then entered into Mendeley. Results: Conclusion: Assistance to cadres can increase cadres{\textquoteright} knowledge and skills in improving nutrition for children, especially toddlers and toddlers. Mentoring and empowering cadres is carried out using various methods such as counseling, training, using various tools and media.

}, keywords = {Baduta Nutrition, Cadres, Mentoring, Two years baby., underweight}, doi = {10.5530/pj.2024.16.155}, author = {Ramli Ramli and Muhammad Syafar and Veni Hadju and Aminuddin Syam and Anwar Mallongi} } @article {2350, title = {Community-Based Electronic Recording and Reporting in Indonesia: Systematic Review}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {August 2024}, pages = {860-864}, type = {Research Article}, chapter = {860}, abstract = {

Background: Implementing electronic-based health information systems in Indonesia has shown a significant increase in the last decade. However, many problems still need to be solved that hinder the effectiveness of this system. Studies describing the implementation of electronic-based data collection, monitoring, and reporting show confusing results. Aim: This review aims to evaluate the implementation of community-based electronic data collection, monitoring and reporting. Method: PRISMA guidelines was used to conduct this review. Databases used to search relevant literature including PubMed, Sciencedirect, Willey Online Library, and Proquest. Authors independently screening and extracted the data from the eligible studies. CASP for qualitative study was used to assess the quality of the study. Result: There are nine studies that matched with the inclusion criteria. Area of recording, monitoring, and reporting including maternal and child health, NCDs, and Tuberculosis. the challenges faced by Indonesia in implementing the ERMR including internet connections, access to electricity, absence of regulations, human resources, facilities, Fragmented application, Age, Pandemic, and lack of communication. Based on those barriers, infrastructure in supporting the implementation of ERMR is the most stated in the studies included. Conclusion: The implementation of ERMR is crucial for the Indonesian government to address immediately, given the significantly substantial benefits for the health status of the Indonesian people. The availability of adequate infrastructure, especially in remote areas, will support satisfactory public health services.

}, keywords = {Health, Indonesia., Monitoring, Recording, Reporting}, doi = {10.5530/pj.2024.16.140}, author = {Rahmat Haji Saeni and Andi Zulkifli Abdullah and Veni Hadju and Ridwan Amiruddin and Agus Bintara Birawida and Suriah and Rika Handayani and Anwar Mallongi} } @article {2339, title = {The Effect of Giving Iodized Salt and Multi Micro Nutrients to Pregnant Women on the Nutritional Status of Pregnant Women in Majene Regency}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {August 2024}, pages = {779-784}, type = {Original Article}, chapter = {779}, abstract = {

Background: Maternal nutritional needs during pregnancy increase due to physiological, metabolic and anatomical changes. If the intake is insufficient, there will be deficiencies in both macro and micro nutrients. Multimicronutrient deficiency will affect the growth and anemia status of pregnant women. Objective: This study aims to determine the effect of giving iodized salt and Multi Micronutrient Supplements to pregnant women on hemoglobin levels, body weight, iodine levels in urine and pregnancy outcomes. Method: This research is an analytical research using an experimental design that controls several nonexperimental variables and there is a control group as a comparison group to understand the effect of treatment. Determining the sample in this study used a random experimental method where 200 pregnant women were used as the research sample. The results showed that there was a significant change or increase in Hb levels (p=0.006; \<0.000; \<0.000), body weight (p=0.001; \<0.000; \<0.000), lila (\<0.0015; \<0.000; \<0.000 ), Iodine levels (\<0.000; \<0.000; \<0.000), between the group given iodized salt and MMS and the group given MMS. In this study, in the group of pregnant women who received iodized salt and MMS intervention, on average there was an increase or change in HB levels, iodine levels, mother{\textquoteright}s weight, baby{\textquoteright}s weight and abdominal length and circumference compared to those who received MMS. for pregnant women is to regularly maintain nutritional intake during pregnancy, especially consuming iodized salt and MMS which is beneficial for the health of pregnant women and the baby they are carrying.

}, keywords = {Pregnant women; Iodine Salt; Multi Micro Nutrient Supplement; Nutritional status.}, doi = {10.5530/pj.2024.16.129}, author = {Darmin Dina and Nurhaedar Jafar and Veni Hadju and Hasnawati Amqam and Ridwan Amiruddin and Wahiduddin and Anwar Mallongi and Apik Indarty Moedjiono and Anang S. Otoluwa and Yulianah Sulaiman} } @article {2403, title = {Effect of Moringa Oleifera Plus Royal Jelly Capsules in The Gestation Age and Placenta Weight of Newborns in Indonesia}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {October 2024}, pages = {1177-1182}, type = {Research Article}, chapter = {1177}, abstract = {

Background: The incidence of adverse birth outcomes (ABO) in low- and middle-income countries (LIMC) remains significantly elevated. Moringa oleifera (MO), rich nutritional profile, offers to reduce ABO. Therefore, this study aimed to evaluate the impact of MO plus royal jelly capsules on the gestational age and placental weight of newborns in Indonesia. Materials and Methods: A quasi-experimental design setup in the Banggai district, Central Sulawesi Province. The study used a purposive sampling of 80 pregnant women from each sub-district. Moilong District received MRJ, while South Batui District was the Multiple Micronutrient Supplement (MMS) control group. Both groups took one capsule daily for six months. Data analysis using SPSS v28 for Windows, including Chi-square/Fisher{\textquoteright}s exact test, Kolmogorov- Smirnov test, Mann-Whitney test, and ANCOVA, with a significance level of p \< 0.05. Results: The demographic characteristics in both groups were similar (p \> 0.05), except for BMI (p=0.031). Pregnancy outcomes data were also identical (p \> 0.05). The Mann-Whitney test did not show a significant difference (p = 0.696) in the gestational age of delivery between the groups. However, there was a significant difference (p \< 0.05) in the PW variable within the MRJ group, as shown by the Mann-Whitney test. After adjusting for BMI in PW, the ANCOVA test indicated a significant difference (p = 0.001). Conclusions: The study concludes that MRJ and MMS interventions are effective and safe in preventing ABO in newborns based on gestational age and placental weight.

}, keywords = {Adverse Birth Outcomes, Moringa oleifera, Multiple Micronutrient Supplement, Pregnancy outcomes, Pregnant women}, doi = {10.5530/pj.2024.16.192}, author = {Lina Fitriani and Citrakesumasari and Veni Hadju and Sudirman Nasir and Apik Indarty Moedjiono and Masyitha Muis and Nurpudji Astuti Taslim and Sri Sumarni and M.Bambang Uswatul Firdaus} } @article {2264, title = {Intercorrelations among Hemoglobin Level, Physical Fitness, and Cognitive Score in Adolescent Girls: A Cross Sectional Study in Banggai District, Indonesia}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {April 2024}, pages = {405-409}, type = {Research Article}, chapter = {405}, abstract = {

Iron deficiency anemia in adolescent girls can cause decreased concentration, cognitive levels and fitness. In the long term it will have an impact on low productivity and school achievement. This study aims to analyze the correlations between hemoglobin level, physical fitness and cognitive score in Anemic adolescent girls. The research design was cross-sectional, with a sample of adolescent girls aged 12{\textendash}18 years (n=139). Iron status was determined by hemoglobin levels using Hemocue. Cognitive function was measured using the Culture Fair Intelligence Test (CFIT), memory scores using the Intelligenz Structure Test (ITS), and physical fitness based on the predicted VO2max using the Bleep Test. Correlation analysis uses Pearson correlation analysis. The research results showed that overall 58.3\% of students experienced anemia, of which 64.1\% experienced mild anemia and 32.1\% experienced moderate anemia. The average value of hemoglobin levels in respondents was 11.6 mg/dl. The mean predicted VO2 max is 25.3 kg/ m2 and kognitif score 81,02 and memori score 11,01. Pearson{\textquoteright}s test results showed that there was a significant positive correlation between hemoglobin levels and predicted VO2 max (r = 0.28, p\<0.05) and memori score (r = 0.31, p\<0.05). There was a weak correlation between hemoglobin levels and kognitif score (r=0.17, p=0.053). Conclusion: There is a significant relationship between hemoglobin levels and physical fitness and cognitive function. Therefore, an intervention program is needed to increase Hb levels in adolescent girls

}, keywords = {Adolescent girl, Anemia, Hemoglobin level, kognitif, Physical Fitness}, doi = {10.5530/pj.2024.16.63}, author = {Risma Risma and Veni Hadju and Andi Zulkifli and Healthy Hidayanti and Syamsiar S.Russeng and Apik Indarty and Abdul Salam and Toto Sudargo and Abdul Fandir and Masrif Masrif} } @article {1999, title = {The Effect of Moringa Leaf Extract Intervention Since Preconception Period on the Prevention of Oxidative Stress in Pregnant Women and Adverse Pregnancy Outcomes}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {April 2023}, pages = {310-314}, type = {Original Article }, chapter = {310}, abstract = {

Background: Oxidative stress occurs due to an imbalance of oxidants and anti-oxidants and is often associated with poor pregnancy outcomes. Therefore, additional supplementation is needed since the preconception period to prevent oxidative stress and poor pregnancy outcomes. This study aims to examine the effect of supplementing Moringa leaf extract on the prevention of oxidative stress in pregnant women and poor pregnancy outcomes. Methods: This study is an observational study with a prospective cohort study design. The research subjects were third trimester pregnant women consisting of 2 groups, namely the control group who only received Iron-Folic Acid (IFA) supplements (n = 30) and the group that received moringa leaf extract and IFA supplements (n = 26). Then an examination of Malondialdehyde (MDA) levels as a biomarker of oxidative stress was carried out using the ELISA (enzyme-link immune sorbent) method, followed by pregnancy outcomes including birth weight and birth length. Data were analyzed by unpaired t test. Results: The results showed that there were no significant differences in the levels of MDA, birth weight and birth length in the two groups with a p value \> 0.05. Nevertheless, MDA level in IFA group was 49.25 nmol/ml higher than Moringa + IFA group which was 47.58 nmol/ml. Likewise, the average of birth weight and birth length in Moringa group were 3042.3 grams and 48.62 cm higher than IFA group which were 2993.7 grams and 48.23 cm. Malondialdehyde levels were also higher in women who had babies with birth weight \< 2500 grams was 49.48 nmol/ml and birth length \< 48 cm was 49.13 nmol/l compared to birth weight >= 2500 grams was 48.50 nmol/ml and birth length >= 48 cm was 48.62 nmol/ml but there was no significant difference in the two groups (p\>0.05). Conclusion: Oxidative stress in pregnant women tends to be associated with poor pregnancy outcomes. Moringa leaf extract supplementation since preconception can prevent increased oxidative stress and improve pregnancy outcomes.

}, keywords = {Malondialdehyde, Moringa oleifera, Oxidative stress, Pregnancy outcomes.}, doi = {10.5530/pj.2023.15.45}, author = {Rahma and Veni Hadju and A. Arsunan Arsin and Aminuddin Syam and Anwar Mallongi and Abd. Farid Lewa and Haerani Harun and Miranti} } @article {1995, title = {The Effect of Preconcenption Moringa Leaf Extract Supplementation on Cotinine Serum Levels in Pregnant Women Exposed to Tobacco Smoke}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {April 2023}, pages = {290-293}, type = {Original Article }, chapter = {290}, abstract = {

Background: Moringa oleifera is known for its nutrition content, antioxidant and medical benefit. Tobacco smoke contains various toxic substance and can affect the pregnancy. To reduce the tobacco smoke effect on pregnancy outcome good nutrition is needed. Objective: This study aims to assess the effect of Moringa leaf extract on serum cotinine levels in pregnant women exposed to second-hand tobacco smoke. Method: This is an observational study with a prospective cohort study design the study population was pregnant women which were divided by 2 groups, first group received IFA supplements only (n = 30) and the second group receive IFA and Moringa leaf extract supplements (n = 26). The tobacco smoke exposure data collected with questionnaire, and cotinine serum by blood sample. The tobacco smoke exposure and cotinine serum levels were compered between the two groups. Results: The tobacco smoke exposures at home were higher in MO+IFA group pregnant women then the IFA group pregnant women (p\<0,05). The cotinine serum levels in both groups were found not significantly different (p=0,535). These results indicate that pregnant woman with high exposure of tobacco smoke who MO receive have similar cotinine serum levels with the pregnant woman with lower exposure of tobacco smoke. Conclusion: Moringa leaf extract supplementation to pregnant women with high tobacco smoke exposure has serum cotinine levels similar to pregnant women with lower exposure to tobacco smoke.

}, keywords = {Cotinine, Moringa oleifera., Preconception, Tobacco smoke}, doi = {10.5530/pj.2023.15.41}, author = {Haerani Harun and Anwar Daud and Ridwan Amiruddin and M Sabir and Veni Hadju and Anwar Mallongi and Rahma and Miranti and Tamrin Talebe and M. Faris} } @article {2198, title = {The Effect of Ramania Leaves Extract Gel (Bouea macrophylla Griff) on the Number of Osteoblast (in vivo Study of Post Extraction in Wistar Rats (Rattus norvegicus))}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {December 2023}, pages = {1219-1223}, type = {Original Article}, chapter = {1219}, abstract = {

Ramania leaves extract contains secondary metabolite compounds such as flavonoids, steroids, phenols and terpenoids which can be used as an alternative medicine for socket wound healing. Flavonoids have anti-inflammatory and antioxidant properties that can accelerate wound healing and can stimulate the formation of osteoblasts. Analyzing the differences in the number of osteoblasts in the negative control group, positive control given aloe vera gel 15\% and ramania leaf extract gel 15\% on day 5, 7 and 14. This study used true experimental design with posttest-only control design, using 27 rats divide into 3 groups. The experimental animals were sacrificed on days 5, 7 and 14 for histopathological observations. Two-Way ANOVA test results obtained p value = 0.013 \<0.05, which indicates that there is a significant difference between the use of 15\% ramania leaf extract gel 15\% and the number of osteoblasts on days 5, 7 and 14. Bonferroni{\textquoteright}s Post Hoc test showed a difference. The number of osteoblasts was significant among the negative control group with ramania leaf extract gel 15\%. Ramania leaf extract gel 15\% was proven to be able to increase the number of osteoblasts and has the potential as an alternative medicine for socket healing after tooth extraction.

}, keywords = {Bouea macrophylla Griff, Flavonoids, Osteoblast, Ramania leaf extract gel, Secondary metabolite, Tooth extraction}, doi = {10.5530/pj.2023.15.221}, author = {Irham Taufiqurrahman and Siti Hajar Norma Gupita and Beta Widya Oktiani and Isyana Erlita and Andi Zulkifli and Veni Hadju and Anwar Mallongi and Eko Suhartono} } @article {2195, title = {The Miracle of Moringa Oleifera Leaves for the Prevention of Anemia: A Literature Review}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {December 2023}, pages = {1258-1261}, type = {Review Article}, chapter = {1258}, abstract = {

Background: Moringa oleifera leaves contain very rich compounds that include nutrients, minerals, vitamins, amino acids, and many other compounds with numerous benefits for humans. This literature review discusses the benefits of Moringa oleifera leaves in preventing anemia. Methods: This review is a narrative review using the research of international journal sources from databased, national journals in the last ten years. The keywords anemia, hemoglobin, and Moringa oleifera/M. oleifera leaves were used. Based on the 35 journals reviewed, 12 studies were included in this review. Results: The literature results show a positive relationship between Moringa leaf extract and an increase in the value of hemoglobin levels, with a p-value \<0.05. However, this review found other benefits of Moringa oleifera leaf extract, such as improving the morphology of damaged red blood cells and antioxidants. It has become an alternative in the treatment of anemia. Conclusions: The nutrient content in Moringa leaf extract plays a significant part in increasing hemoglobin levels in the blood. Other factors that can increase the risk of anemia are micronutrient deficiency, infectious diseases (HIV/AIDS, tuberculosis, and malaria), worm infections, and genetic disorders. (25) We recommend conducting an experimental study to compare two groups given Moringa leaf extract and multi-micronutrient tablets to get more effective results in lowering the prevalence of anemia.

}, keywords = {Anemia, Moringa oleifera leaf extract}, doi = {10.5530/pj.2023.15.228}, author = {Dwi Wahyu Balebu and Ridwan Aminuddin and Veni Hadju and Arsunan Arsin and Nurhaedar Jafar and Herawati and Anwar Mallongi} }