@article {1842,
	title = {Amino Acid and Proximate Analysis of Type-1 Collagen from Sea Cucumber and Tilapia-Skin and its Potential Application as Artificial Tendon},
	journal = {Pharmacognosy Journal},
	volume = {14},
	year = {2022},
	month = {August 2022},
	pages = {358-361},
	type = {Original Article },
	chapter = {358},
	abstract = {<p class="rtejustify">Tendon injury is a medical indication that requires surgical therapy and prolonged recovery. Collagen plays a crucial role in the wound healing process. Collagen maintains homeostasis, interacts with platelets, and enhances cellular components. Most living organisms consist of collagen components as fibrillar proteins. In this study, the potential properties of type-1 collagen from sea cucumber and Tilapia-skin were evaluated depend on proximate analysis, amino acid composition, and moisture-absorption ability. The result showed that Tilapia-skin has a higher protein and fat composition compared to the sea cucumber. In contrast, moisture, ash, and yield composition showed higher for sea cucumber compared to Tilapiaskin. Meanwhile, based on amino acid analysis was revealed that proline, alanine, methionine, isoleucine, leucine, phenylalanine, and lysine were lower on sea cucumber compared to Tilapia-skin. In conclusion, both type-1 collagen material from sea cucumber and Tilapia-skin might be developed as a biomaterial for tendon injury. It is crucial that further studies be carried out to emphasize the potential of biodegradable and bio-replaceable materials using the<em> in vivo </em>model.</p>
},
	keywords = {collagen, Key words: Artificial tendon, Marine biodiversity, Sea cucumber, Tilapia-skin},
	doi = {10.5530/pj.2022.14.107},
	author = {Arifia Safira and Cinta Atsa Mahesa Rani and Roro Ayu Puspitasari and Anindyta Kirana Putri Ayuningtyas and Yayang Amru Mahendra and Agus Purnomo and Faisal Fikri and Shekhar Chhetri and Muhammad Thohawi Elziyad Purnama}
}
