@article {1624, title = {Isolation and Structural Characterization of Compounds from Blumea lacera}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {July 2021}, pages = {999-1004}, type = {Research Article}, chapter = {999}, abstract = {

Background: The medicinal plants consider as a rich resource of ingredients which can be used in drug development and synthesis. Blumea lacera (Burm. f.) DC. is generally used in traditional medicine for the treatment of cough, bronchitis, dysentery, wound healing. The aim of this study is to isolate and identify the compounds from the aerial parts of Blumea lacera. Methods: The aerial parts of B. lacera were dried, powdered and extracted using EtOH, and the concentrated extract was partitioned in succession with n-hexane, CH2Cl2, and EtOAc. From the EtOAc fraction, the compounds were isolated through column chromatography and their chemical structures were elucidated by NMR spectroscopy and confirmed by comparison of their NMR data with literature data. Results: Repeated column chromatography of the EtOAc-soluble fraction from the aerial parts of B. lacera resulted in the isolation of β-sitosterol (1), campesterol (2), artemetin (3) and acid paracatechuic (4).

}, keywords = {Asteraceae, Blumea lacera, Column chromatography, Flavonoid}, doi = {10.5530/pj.2021.13.129}, author = {Xuan Phong Pham and Tran Thi Tuyet Nhung and Hoai Nam Trinh and Do Minh Trung and Dang Truong Giang and Binh Duong Vu and Nguyen Trọng Diep and Nguyen Van Long and Van Thu Nguyen and Chu Van Men} }