@article {1802, title = {Peel-off Mask Formulation from Stem of Sempeng (Nepenthes gracilis) as Anti Acne Against Propionibacterium acnes Bacteria}, journal = {Pharmacognosy Journal}, volume = {14}, year = {2022}, month = {June 2022}, pages = {565-570}, type = {Research Article}, chapter = {565}, abstract = {

Introduction: Stem of Sempeng (Nepenthes gracilis), which contain saponin and tannin has been known had antibacterial activity against Propionibacterium acnes that usually improve severe of acne. Acne is a skin disease characterized by chronic inflammation in the polisebasca that often occurs in adolescence. Aims and Objective: The aims of this research are to develop and test a peel-off mask prepared from stem of Sempeng extracts, which has antibacterial activity against Propionibacterium acnes. Materials and Methods: Stem of Sempeng was extracted with soxhletation method by ethanol 96\%. The extract was formulated into peel-off mask with different extract concentration (0, 1, 5, 10, 15) \%. Then the inhibition test of the extract and peel-off mask was measured against bacteria Propionibacterium acnes. The data analysis technique used in this study was to measure the zone diameter on a petri dish using a caliper with a millimeter (mm) unit and presented in tables and photos, the results of the inhibition zone measurement were compared with the classification of the response of the extract barrier to the growth of Clinical and Laboratory Standards Institute (CSLI) standard bacteria. Results: The result showed that the inhibition zone of the peel off mask preparation of sempeng stem extract in F1 and F2 formulations with extract concentrations of 1\% and 5\% are categorized as resistant, which means that the Propionibacterium acnes bacteria has a low level of sensitivity so that a large inhibition zone is not formed. Whereas in the F3 formulation with a concentration of 10\% is categorized as an intermediate, which means in this concentration, the mask can inhibit the growth of the inhibition zone Propionibacterium acnes bacteria which is formed quite well, but in this category it will require repeated use or with high doses of use. Then in the F4 formulation with a concentration of 15\%, it is categorized as susceptible, which means the mask have a good inhibitory resistance zone, this shows that the increase in high concentration, the greater the inhibition zone as well. Conclusion: The peel off mask from ethanol extract of Sempeng stem is able to inhibit the growth of Propionibacterium acnes bacteria. The peel mask preparation with concentration 1\%, 5\%, 10\% and 15\% forms a clear zone around the disc which means that this peel off mask formulation has activity to inhibits Propionibacterium acnes bacteria and is included in the category of susceptible interpretation according to the CLSI standard.

}, keywords = {Nepenthes gracilis stem extract, Peel-off mask, Propinibacterium acnes.}, doi = {10.5530/pj.2022.14.72}, author = {Rezqi Handayani and Nurul Qamariah} } @article {1938, title = {The Serum Formulation of Hati Tanah Tuber Ethanol Extract from Central Kalimantan}, journal = {Pharmacognosy Journal}, volume = {14}, year = {2022}, month = {January 2023}, pages = {978-982}, type = {Research Article }, chapter = {978}, abstract = {

Introduction: Lately, the use of natural cosmetics can have a good effect on the skin. One of them is traditional beauty treatments. The Serum is a preparation with low viscosity, because of its low viscosity serum is categorized as an emulsion preparation. From the results of research that has been carried out, ethanol extract of Hati Tanah tuber has great potential as an anti-acne because it can inhibit the growth of acne-causing bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, Propionibacterium acnes. With the innovation of serum ethanol extract of Hati Tanah tuber, it can be an option for the community later in the treatment of acne. Methods: The formulation is made in 4 (four) formulas with different concentrations of the main ingredients used. Next is to weigh all the ingredients needed according to each formula. Then physical properties test performed. a) Organoleptic test; b) Homogeneity Test; c) pH test; d) Spreadability Test and e) Adhesion Test. Results: The organoleptic test was carried out directly by looking at the shape and color and smelling the serum preparation of the ethanol extract of Tanah Hari tubers. The test results show that at F0 (0\%) the color is clear, for F1 (0,5\%) it is quite pale pink, F2 (1\%) is bright pink and F3 (5\%) is dark red. For scent organoleptic, F0 indicates no scent, for F1 and F2 there is a distinctive scent from the Hati Tanah tuber which is slightly pungent, while F3 shows a pungent aroma typical of the Hati Tanah tuber. The resulting serum has a thick texture at F0 and F1, a watery texture at F2 and a thinner texture at F3. All of the formulas have met the physical test requirement of organoleptic properties, homogeneity, pH, and adhesion test. Conclusion: The simplicia of Hati Tanah tuber can be made into an innovative cosmetic preparation in the form of serum with a concentration of 0,5\%, 1\% and 5\%. From the results of testing the physical properties of the formulations, all of the formulas have met the physical test requirement of organoleptic properties, homogeneity, pH, and adhesion test.

}, keywords = {Formulation, Hati Tanah Tuber Ethanol Extract., Serum}, doi = {10.5530/pj.2022.14.199}, author = {Nurul Qamariah and Rezqi Handayani and Jessika Maretania} } @article {929, title = {The Potential Herbs of Medicinal Forests from Central Kalimantan as a Inhibitor of Staphylococcus aureus}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {July 2019}, pages = {740-744}, type = {Original Article}, chapter = {740}, abstract = {

Background: Central Kalimantan is one of the largest provinces in Indonesia with a wealth of medicinal herbaceous plant species. This province was the origin of various medicinal plants such as tabat barito, akar kuning, pasak bumi and some other medicinal plants that were useful for human health. Methods: This paper explain about inhibitory test extracts etanol of Hati Tanah (Angiotepris Sp) tubers and Sangkareho leaves (Callicarpa longifolia Lam.) in Staphylococcus aureus bacteria with concentration 1\%, 5\%, 10\%, and 15\%. Both plants has been utilized by the community as a traditional medicine to treat minor to moderate injuries such as postpartum. Results: The results for extract Hati Tanah was 15.63 mm, 16.97 mm, 25.42 mm, 28.40 mm and the results for and Sangkareho leaves was 1 mm, 2.68 mm, 3.9 mm, 6.2 mm. Inhibitory test studies have also been performed on the N-Butanol fraction from ethanol extract Hati Tanah tubers of the soil at the same concentrations and bacteria. The inhibited zone results was 15.65 mm, 23.20 mm, 24.15 mm, 26.25 mm. Conclusion: Medicinal forest plants origin of Central Kalimantan is Hati Tanah tubers and Sangkareho leaves has potential as a traditional medicine in inhibiting and killing Staphylococcus aureus bacteria.

}, keywords = {Inhibitory test, Medicinal forest, Staphylococcus aureus, Traditional medicines}, doi = {10.5530/pj.2019.11.117}, author = {Rezqi Handayani} }