@article {857, title = {Evaluation of Anti-psoriatic Potential of the Fruit Rind of Punica granatum L.}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {May 2019}, pages = {466-468}, type = {Original Article}, chapter = {466}, abstract = {

Background: Pomegranate (Punica granatum L.) is universally known for its therapeutic properties due to its potential bioactive compounds. However, there is no established scientific study on antipsoriatic activity of pomegranate fruit rind. The aim of the study is to evaluate the anti-psoriatic activity of the isolated compounds and the extract from the fruit rind of P. granatum. In our previous study, the isolated compounds were evaluated for antioxidant potential. In continuation to the previous investigation, the present study is taken up to evaluate the extract and compounds for in vitro anti-psoriatic activity. Methods: Chromatographic techniques were employed to isolate the compounds from the aqueous acetone extract and in vitro anti-psoriatic activity was determined by thymidine phosphorylase inhibition assay. Results: From previous phytochemical investigation, three compounds were identified as Punicalagin, 2,3(S)-hexahydroxydiphenoyl-D-glucose and Punicalin. In the present study, the extract and the compounds were evaluated for anti-psoriatic activity. The results reveal that the isolated three compounds showed inhibitory activity of 89\% to 95\% against thymidine phosphorylase. Aqueous acetone extract also exhibited 87\% inhibition. Conclusion: Punica granatum is an ideal plant for further investigation to prove its anti-psoriatic activity.

}, keywords = {Anti-psoriatic activity, Punica granatum, Thymidine phosphorylase inhibition}, doi = {10.5530/pj.2019.11.73}, author = {Janani Jacob and Gopalan R and Lakshmanaperumalsamy P and Ramanaiah Illuri and Damaji Bhosle and Gopala Krishna Sangli and Deepak Mundkinajeddu} } @article {994, title = {An Overview of Phytochemical and Pharmacological Potentials of Punica granatum L}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {September 2019}, pages = {1167-1171}, type = {Review Article}, chapter = {1167}, abstract = {

Pomegranate (Punica granatum) is considered as {\textquotedblleft}A pharmacy unto itself{\textquotedblright} in Ayurvedic medicine and also used in several other systems of medicine. The plant belongs to the family Lythraceae containing pomegranate as a predominant species. Various parts of the plant exhibits significant pharmacological activities due to its wide range of potential bioactive compounds. Many biological activities proved its antioxidant, anticancer, anti-inflammatory, antimicrobial, anti- athersclerotic, antidiabetic actions and many more. This article provides a review of phytoconstituents of Punica granatum and its diverse array of biological properties.

}, keywords = {Bioactive compounds, Lythraceae, Pharmacological activities, Phytoconstituents, Punica granatum, Traditional medicine}, doi = {10.5530/pj.2019.11.181}, author = {Janani Jacob and Rajiv P and Gopalan R and Lakshmanaperumalsamy P} }