@article {1921, title = {The Ethanolic Extract of Rhinachantus nasutus (L.) Kurz Flower has Antioxidant, Anti-Gout, and Antibacterial Potential}, journal = {Pharmacognosy Journal}, volume = {14}, year = {2022}, month = {December 2022}, pages = {867-872}, type = {Research Article }, chapter = {867}, abstract = {

The goal of this research was to explore the potential of Rhinachantus nasutus (L.) Kurz (RnLK) flower extract as an antioxidant utilizing the ferric reducing antioxidant power (FRAP) method; the possibility that it might be used as a treatment for gout by employing the 2,4,6-tribromo-3-hydroxybenzoic acid (TBHBA) technique, as well as the possibility that it could be used as an antibacterial agent against E. coli and B. subtilis. Results: The IC50 value for the extract{\textquoteright}s ability to serve as an antioxidant is 8.62{\textpm}0.006 mg/L, indicating that it is quite effective. In addition, the extract of ethanol possesses highly potent anti-gout properties, being capable of bringing about a 81.95{\textpm}0.1\% reduction in uric acid levels. In spite of this, the antibacterial properties of E. coli as well as B. subtilis bacteria were not particularly robust. Conclusion: The RnLK flower has the potential to produce alternative chemicals with the ability to reduce blood uric acid levels, but according to the results of the test, the antibacterial activity has little impact on E. coli and B. subtilis.

}, keywords = {Antibacterial, FRAP, RnLK, TBHBA}, doi = {10.5530/pj.2022.14.181}, author = {Candra Irawan and Berna Elya and Muhammad Hanafi and Fadlina Chany Saputri} }