You are hereJan 30,2010, Volume 2, No. 5 / In Vitro Antioxidant Activity of Methanolic Extract of Aerial Parts of Salvia splendens (Scarlet Sage) / In Vitro Antioxidant Activity of Methanolic Extract of Aerial Parts of Salvia splendens (Scarlet Sage)

In Vitro Antioxidant Activity of Methanolic Extract of Aerial Parts of Salvia splendens (Scarlet Sage)


Order of Publishing in Issue: 
2
Volume :2
Issue :5
Regular
January, 2010
Page No: 
7-12
Authors: 
Mahesh Kumar P.*[1], Sasmal D.[2], Mazumder Papiya mitra[2]
Address: 
[1] GITAM Institute of pharmacy, GITAM University, Visakhapatnam
[2] Department of pharmaceutical sciences BIT, Mesra, Ranchi.
Email-ID: 
noone@noone.com

Abstract:In vitro antioxidant activity of methanolic extract of aerial parts of Salvia splendens was determined by DPPH free radical scavenging, hydrogen peroxide scavenging and superoxide anion scavenging assays. Ascorbic acid and butylated hydroxyl anisole were used as standard antioxidants for the analysis. All the analysis was made with the use of UV–Visible spectrophotometer (Schimadzu uv-vis 1700). The methanolic extract of aerial parts of Salvia splendens had shown very significant DPPH (1, 1, Diphenyl-2-picryl-hydrazyl) radical scavenging, hydrogen peroxide scavenging, and superoxide anion scavenging activity compared to standard antioxidants. The Ic50 values of methanolic extract in DPPH radical scavenging, hydrogen peroxide scavenging and superoxide anion scavenging assays are found to be 460 ?g/ml, 358 ?g/ml and 527?g /ml respectively

Keywords: 
Antioxidant, Salvia splendens, DPPH, Hydrogen peroxide, superoxide anion.

 

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