In vitro antioxidant activity of Entada pursaetha, Toddalia aculeata, and Ziziphus mauritiana.

Abstract:

The antioxidant activity of the crude methanolic extract of the seeds of Entada pursaetha, the stem of Toddalia aculaeta, and the fruit of Ziziphus mauritiana was investigated. The total phenolic composition of methanolic extract was calculated to be 5.5mg catechol equivalents/g of sample. Antioxidant activity of the extract was evaluated on the basis of ability of scavenging free radical and hydroxyl radical with the Ic 50 values 2.12mg/ml and 1.034mg/ml respectively. Total antioxidant capacity of crude plant extract was found to be 1.43mg ascorbic acid equivalents at 250?g/ml extract concentration. The reducing power of the extract increased dose dependently and the extract reduced the most Fe 3+ ions to the extent less than the standard ascorbic acid.