Home | Content | Phytochemical investigation and antimicrobial studies on the leaf extracts of Psoralea corylifolia Linn

Phytochemical investigation and antimicrobial studies on the leaf extracts of Psoralea corylifolia Linn

Order of Publishing in Issue: 
6
Volume :2
Issue :5
Regular
January, 2010
Authors: 
Somasundaram T[1], Chandrasekar S.B[2]*, Bhanumathy M[2] and Vijay Amitharaj R[1]
Address: 
[1]Department of Pharmaceutical Chemistry, Thanthai Roever College of Pharmacy, Perambalur, India.
[2]Natural Remedies Pvt. Ltd., Bangalore, India.

Abstract:

Aqueous and alcoholic extracts from Psoralea corylifolia leaves were screened for the presence of chemically active compounds by standard methods and evaluated for their antimicrobial activity in vitro by disc diffusion method. The results revealed the presence of saponins, tannins, flavonoids, glycosides, carbohydrates, tannins and phenolic compounds, gums and mucilages, fixed oils and fats. Alkaloids were not detected from any of the leaves extract under study. Aqueous and alcoholic extracts exhibited broad-spectrum antibacterial and antifungal activity against Eschericia coli, Pseudomonas aeruginosa, Staphylococcus pyogenes and Candida albicans. Alcoholic extract is better than that of aqueous extract of P. corylifolia leaves in respect to their antimicrobial activity and the broad spectrum of activity makes it a promising indigenous drug.

Keywords: 
Alcoholic extract, Antimicrobial activity, Aqueous extract, Leaves, Psoralea Corylifolia.
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