The in vitro antibacterial activity of the extracts of the bryophytes was assessed using agar-well diffusion method
against three bacterial strains. The bryophyte extracts were prepared in methanol and dichloromethane. Inhibition of
bacterial growth was compared with that of ampicillin and tetracycline as positive control and solvents as negative
control. The methanol and dichloromethane extracts of Plagiochasma intermedium, Asterella wallichiana and Targionia
hypophylla had potential activity against all the microorganisms tested. The dichloromethane extract of P. intermedium,
methanol extracts of A. wallichiana and T. hypophylla also showed good results. Among all the bryophytes investigated
for in vitro antimicrobial activity the extracts of T. hypophylla showed most promising results than that of all others
while the extracts of Cyathodium cavernarum were rather inactive.