TY - JOUR T1 - Pharmacognostic and Pharmacological Evaluation of Hyssopus officinalis L. (Lamiaceae) Collected from Kashmir Himalayas, India JF - Pharmacognosy Journal Y1 - 2018 A1 - Akanksha Srivastava A1 - Kuldeep Awasthi A1 - Bhanu Kumar A1 - Ankita Misra A1 - Sharad Srivastava KW - Antioxidant KW - DPPH KW - HPTLC KW - Hyssopus officinalis KW - Phenolic acids AB -

Introduction: Hyssopus officinalis L. is a well-known herb for its culinary and medicinal significance. The purpose of this study was to perform the pharmacognostic evaluation. Methods: Physicochemical and phytochemical analysis, HPTLC quantification and in vitro antioxidant and antidiabetic activity were done. Results: Preliminary screening revealed the presence of phytomolecules such as alkaloid (0.99%), tannin (1.75%), sugar (1.96%) and starch (0.68%). Total phenolic and flavonoid content were found to be 2.32% and 1.16% respectively. HPTLC quantification data showed that the content of ferulic acid (0.034%) was higher than caffeic acid (0.0064%) on dry weight basis The IC50 value for the in vitro DPPH radical scavenging assay was 0.50 μg/ml and in vitro anti diabetic assay displayed IC50 value of 0.8366 mg/ml. Conclusion: The study suggests presence of considerable amount of phenolic acids and antioxidant activity in the plant which supports its use in the traditional systems of medicine.

VL - 10 UR - http://fulltxt.org/article/652 IS - 4 ER -