TY - JOUR T1 - Encouraging Leads from Marine Sources for Cancer Therapy A Review Approach JF - Pharmacognosy Journal Y1 - 2020 A1 - N Srinivasan A1 - S Dhanalakshmi A1 - P Pandian KW - Algae KW - Anti-cancer activity KW - Marine sponges KW - Natural sources AB -

Cancer is one of the dreadful illnesses that cause mortality in many individuals around the world. Present cancer treatments generally include surgery, radiation therapy with chemotherapy. One of the primary sources of anticancer drugs are natural products that exhibit impressive potential in medicines. Plant and microbial secondary metabolites are an important source for cancer drug development. The ocean has an immense collection of flora and fauna overflowing with natural compounds having potent pharmaceutical significance. Marine bioprospecting has just started recently hence, marine ecosystem has not yet been explored properly. Nearly 68 percent of the drugs derived from marine sources are utilized for cancer and the remaining are utilized for inflammation, pain relief etc. Ongoing advancement in synthetic processes has helped in solving the limitations caused due to the complicated structure of natural products. Unlimited potent sources of compounds that can be isolated having diverse structures are found in the marine biodiversity. Only 1% of the marine microorganisms have been distinguished till now. Coral reefs and mangrove ecosystem have been focused for bioprospecting on the grounds that they have an elevated level of biodiversity. This review focuses on pharmacologically active anti-cancer lead discovery from marine ecosystem. The review has also tried to describe the structure

VL - 12 IS - 6 ER -